After nearly four decades together, Ben (John Lithgow) and George (Alfred Molina) finally tie the knot in an idyllic wedding ceremony in lower Manhattan. But when George loses his job soon after, the couple must sell their apartment and - victims of the relentless New York City real estate market - temporarily live apart until they can find an affordable new home. While George moves in with two cops (Cheyenne Jackson and Manny Perez) who live down stairs, Ben lands in Brooklyn with his nephew (Darren Burrows), his wife (Marisa Tomei), and their temperamental teenage son (Charlie Tahan), with whom Ben shares a bunk bed. While struggling with the pain of separation, Ben and George are further challenged by the intergenerational tensions and capricious family dynamics of their new living arrangements.

Amy, a naive college graduate who believes she's destined to be a great poet, begrudgingly accepts a job at a sex shop while she pursues a mentorship with reclusive writer Rat Billings.

The story of Bettie Page, uber-successful 1950's pin-up model, one of the first sex icons in America, and the target of a Senate investigation (based on her bondage photos).